Wang A, Lu L, Fan J, et al. - Researchers sought to determine the best therapeutic recommendations for superficial esophageal squamous cell carcinoma (sESCC), and for this purpose, they summarized the patterns of lymph node metastasis evaluated by three-field lymphadenectomy in sESCC in their institute with a duration of 12 year. A link was identified between the involved lymph node region and tumor location, however, the most vulnerable region was upper mediastinal and perigastric region. A rise in the incidence of lymph node metastasis was observed in association with the depth of tumor invasion. The identified independent predictors for cervical lymph node metastasis were: lymphatic invasion, tumor location and upper mediastinal lymph node involvement. As per findings, the best indication for endoscopic mucosa resection was tumors invading till proper mucosa. It was important to perform mediastinal-abdominal lymphadenectomy for treating sESCC invading beyond proper mucosa. Cervical lymphadenectomy might be avoided in cases without lymphatic invasion when there was negative upper mediastinal lymph node.