Kim SI, et al. - Experts explored whether genetic alterations in the LYL1 gene (such as amplification) could affect the survival outcomes in patients with uterine corpus endometrial carcinoma (UCEC). Researchers analyzed clinicopathologic characteristics and corresponding genomic data from The Cancer Genome Atlas database in 370 patients with UCEC. They reported that LYL1 gene amplification was related to other poor prognostic factors and correlated with upregulation of cancer-related pathways, despite not being identified as an independent prognostic factor in UCEC.