Lung function deterioration predicts elevated troponin levels in apparently healthy individuals throughout a 5-year follow-up
Respiratory Medicine Jun 12, 2019
Krubiner M, et al. - Among apparently healthy individuals, researchers focused on the inter-relationship between lung function and high-sensitive cardiac troponin T (hs-cTnT) and the alterations over time in these two measurements. Participants (n=2,618) with normal lung function at baseline were observed over 5 years, and the findings revealed a mean annual forced vital capacity (FVC) deterioration of 31.9 (±91.3) ml/year. An increased risk of having hs-cTnT >5 ng/L was observed in relation to lung function decline >5%. An inverse correlation of delta FVC between two consecutive visits, with an increase of hs-cTnT, was noted. Elevated troponin levels were predicted by the deterioration of lung function. Early subclinical cardiac disease may be signified by the deterioration of lung function.
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