Shen Y, Xu X, Zhang Y, et al. - In this investigation, researchers illustrated clinicopathological features of lung cancer associated with cystic airspaces (LCCA) and studied imaging characteristics associated with pathological invasiveness. Two thoracic radiologists for connection with cystic airspace assessed the preoperative CT scans of 10,835 individuals diagnosed with NSCLC between January 2015 and December 2016. A total number of 123 LCCA patients have been identified and four morphologic patterns have been recognized: I, thin-walled type; II, thick-walled type; III, a cystic airspace with a mural nodule type; and IV, mixed type. According to results, the predominant genetic alterations in each type of LCCAs were EGFR mutations, but no important distinction was discovered among them. Two significant predictors for determining pathological invasiveness were morphological patterns and wall components in LCCA.