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Lower triglyceride levels are associated with better endothelial function

Journal of Clinical Lipidology May 03, 2021

Takaeko Y, Maruhashi T, Kajikawa M, et al. - Researchers investigated whether and how triglycerides, especially low levels of triglycerides, were associated with vascular function. Among 7047 individuals, flow-mediated vasodilation (FMD) was assessed. In 1017 people, nitroglycerine-induced vasodilation was recorded. Based on triglyceride concentrations, participants were split into eight groups: < 50 mg/dL, 50-69 mg/dL, 70-89 mg/dL, 90-109 mg/dL, 110-129 mg/dL, 130-149 mg/dL, 150-199 mg/dL, and ≥ 200 mg/dL. In persons showing triglyceride levels of < 50 mg/dL, significantly higher FMD was detected, vs in those exhibiting triglyceride levels of 50-69 mg/dL, 70-89 mg/dL, 90-109 mg/dL, 110-129 mg/dL, 130-149 mg/dL, 150-199 mg/dL, and ≥200 mg/dL. Participants who had extremely low levels of triglycerides (<50 mg/dL) were identified to have the highest FMD values. Findings demonstrated better endothelial function in relation to lower triglyceride levels.

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