Murphy SP, et al. - The purpose with which authors performed this study was to assess the yields of detecting clinically significant injuries (CSIs) with computed tomography (CT) in >1 anatomic region. The yield for CSI in >1 region seemed low during multiple anatomic region CT imaging for adult blunt trauma evaluation. Selective CT imaging of anatomic regions (instead of reflexive head-to-pelvis CT imaging) could be more appropriate in low-risk populations.