Zhu K, Lewis, JR, Sim M, et al. - Gathered by health record linkage, researchers investigated the dose-response relationships of baseline plasma 25-hydroxyvitamin D (25OHD) with hip DXA BMD at year 1, lumbar spine BMD, and trabecular bone score at year 5, and fracture-related hospitalizations over 14.5 years. Through a secondary analysis of 1,348 women 70 to 85 years old at baseline (1998) from the Perth Longitudinal Study of Aging in Women, investigators found that 27.6% of women experienced any fracture-related hospitalization, and 10.6% experienced hip fracture-related hospitalization during the follow-up. Penalized spline regression models exhibited a reduction in risk with increased 25OHD levels up to 65 nmol/L and 75 nmol/L for hip fracture and any fracture-related hospitalization, respectively. According to findings, 25OHD levels > 50 nmol/L are a minimum public health target and 25OHD levels beyond 75 nmol/L might not have an additional benefit to decrease fracture risk in older white women.