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Low risk of hepatotoxicity from rifampicin when used for cholestatic pruritus: A cross-disease cohort study

Alimentary Pharmacology and Therapeutics Feb 26, 2018

Webb GJ, et al. - Experts coveted an elucidation of the rate and characteristics of rifampicin-induced hepatitis in a mixed aetiology cohort of patients with established liver disease and cholestatic pruritus. Findings suggested that adult patients, including those with jaundice, could be counselled regarding 95% of prescriptions being safe, and the drug cessation being effective where hepatitis occurred, including at long latency due to the efficacy of rifampicin for a significant sub-group of individuals with cholestatic pruritus.
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