Scott SA, Fernandez ML, Kim H, et al. - To gain a better knowledge and improve the care of women having advanced low-grade serous carcinoma (LGSC), researchers undertook this retrospective cohort analysis in 5 Canadian referral institutions from 2000 to 2016 in order to analyze practice patterns and treatment results in this patient population as part of a national initiative. In this study done with 134 patients (stage II-IV) with a median follow-up of 32.4 months, a comparison was performed between four primary treatments: surgery followed by chemotherapy (56%), neoadjuvant chemotherapy (NACT) followed by surgery (27%), surgery alone (9%), and surgery followed by anti-hormone therapy (4%). Worse progression-free survival (PFS) was reported in cases managed with NACT. The variables that showed a significant link with better overall survival/PFS were: lesser residual disease, younger age, and primary peritoneal origin, as revealed in the multivariable Cox regression analysis. No significant difference was seen in progression-free intervals and time to next treatment intervals in patients with relapsed disease following the first relapse regardless of treatment type. Across Canada, the analyzed practice patterns showed notable variations. This emphasizes the necessity for ongoing strategies to measure, assess and obtain optimal patient results for women with advanced LGSC.