Ugarte-Gil MF, et al. - Two hundred and forty-three systemic lupus erythematosus (SLE) patients were included from a single center with at least two visits by the researchers to assess whether low disease activity state (LDAS)/remission could predict better health-related quality of life (HRQoL). For every six months, a visit was performed. In the components of physical health, pain, planning, a burden to others, emotional health, and fatigue, a better HRQoL was predicted by LDAS/remission for the patients of SLE.