Chang, Tsui-Yen, Chen, et al. - This study’s findings demonstrate that the low-density lipoprotein cholesterol (LDL-C)/apolipoprotein B (ApoB) ratio is a superior indicator to ApoB in the diagnosis of individuals with coronary artery calcification (CAC). For CAC, it can be conveniently applied to improve the diagnostic ability of ApoB.

• The results show that the prevalence of patients with coronary calcification is elevated with the quartile values of ApoB levels and low quartile values of LDL-C/ApoB ratios.

• For CAC and severe CAC, the odds ratios were 2.9 [95% confidence interval (CI), 2.2–3.9] and 4.4 (95% CI, 3.3–5.9) among the highest quartile of ApoB compared with the lowest quartile, and 9.5 (95% CI, 8.3–10.9) and 103.0 (95% CI, 56.9–187.8) among the lowest quartile of LDL-C/ApoB ratios compared with the highest quartile.

• It was shown that areas under the curve of ApoB and LDL-C/ApoB ratio for the diagnosis of CAC and severe CAC were 0.591 vs 0.679 and 0.618 vs 0.787, respectively.

• The data indicated that the LDL-C/ApoB ratio was superior to ApoB in terms of diagnosing patients with CAC and severe CAC.