Akter S, Mizoue T, Nanri A, et al. - This study was undertaken to investigate the correlation between low-carbohydrate diet (LCD) score (based on a percentage of energy as carbohydrate, fat, and protein) and the risk of total and cause-specific mortality among Asians. Researchers conducted a prospective cohort study in Japan with follow-up for a median of 16.9 years including 43008 men and 50646 women aged 45-75 years. The Cox proportional hazards model was applied to evaluate the relationship of LCD score, LCD score based on animal sources of protein and fat, and LCD score based on plant sources of protein and fat with risk of mortality. The results of this study exhibited that both LCD with high animal protein and fat and high-carbohydrate diet with low animal protein and fat was correlated with higher risk of mortality. It was indicated that LCD high in plant-based sources of protein and fat was correlated with a lower risk of total and cardiovascular disease mortality.