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Low bone mineral density is associated with coronary arterial calcification progression and incident cardiovascular events in patients with chronic kidney disease

Clinical Kidney Journal Jul 29, 2021

Kim H, Lee J, Lee KB, et al. - Among patients with pre-dialysis chronic kidney disease (CKD), this prospective cohort study was conducted to assess the link between bone mineral density (BMD) and the risk of cardiovascular disease and cardiovascular mortality in this patient population. Study sample comprised 1957 patients with pre-dialysis CKD in stages 1 to 5. Major adverse cardiovascular events (MACE) were assessed as primary outcome. Findings demonstrated a significant link of low BMD with coronary arterial calcification progression as well as with MACE in patients with pre-dialysis CKD.

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