Kranawetter M, et al. - Patients with debulking surgery for primary advanced epithelial ovarian cancer were examined to assess the prevalence of low anterior resection syndrome (LARS) in these patients, as well as possible risk factors for LARS development. In total, they identified 341 patients as eligible; of these, 206 (60.4%) were contacted and complete information obtained. Seventy-eight (37.9%) patients experienced major LARS, 44 (21.4%) patients experienced minor LARS, and 84 (40.8%) patients experienced no LARS. Following debulking surgery (including low anterior resection) in primary advanced epithelial ovarian cancer (EOC) patients, LARS in general and major LARS especially, appears to be a frequent long-term complication. Risk for major LARS was higher for EOC patients with more than one bowel anastomosis during surgery. Time interval between surgery and LARS assessment, type of cytoreductive surgery, and recurrent disease at the time of assessment did not impact the prevalence of LARS.