Goedegebuure WJ, van der Steen M, Kerkhof GF, et al. - Given that 2 years of gonadotropin-releasing hormone analogue (GnRHa), in addition to long-term growth hormone (GH) treatment, can improve adult height in children born small for gestational age (SGA) with persistent short stature, researchers evaluated metabolic and bone health safety of GnRHa/GH treatment for 5 years after GH cessation. A total of 363 young adults born with SGA, previously treated with combined GnRHa/GH or GH-only, were followed at GH cessation for 5 years after reaching adult height and 2 and 5 years afterwards. This study during 5 years after GH cessation shows that adding 2 years of GnRHa treatment to long-term GH treatment for children short in stature born SGA has no adverse effects on early adulthood metabolism and bone health.