Nouri-Mahdavi K, et al. - In this cross-sectional study, researchers examined central structure-function (SF) associations in glaucoma and contrasted contributions of within-session and between-session variability to the total variability of macular optical coherence tomography thickness measurements, as well as tested the assumption that longitudinal within-eye variability of central SF relationships is smaller than between-individual variability. Thirty-eight eyes (20 normal or glaucoma individuals) had ×3 macular images per session over 3 sessions, and superpixels thickness measurements for ganglion cell layer, ganglion cell/inner plexiform layer, ganglion cell complex, and full macular thickness have been exported. Over time, within-session variability accounts for most of the macular thickness variability. Findings suggested that longitudinal within-eye SF variability is less than between-individual variability. Study of within-eye SF relationships might help doctors better understand SF linking in glaucoma and assist refine progression algorithms.