Cole M, et al. - Researchers longitudinally assessed clustering of chronic sinonasal and related symptoms using exploratory factor analyses (EFA), considering approaches to chronic rhinosinusitis (CRS) symptom measurement do not specify how to measure symptoms and treat specified sinonasal symptoms as generally interchangeable. The same 5 factors (blockage and discharge, pain and pressure, asthma and cold/flu symptoms, smell loss, and ear and eye [mainly allergy] symptoms) were identified in 5 EFAs. Symptom frequency, severity, and degree of bother determined clustering. They found that despite a single underlying latent construct implied by the current approaches to symptom characterization in CRS, there are at least 3 latent constructs that are relevant to CRS.