Long-term survival after invasive or conservative strategy in elderly patients with non-ST-elevation myocardial infarction: A prospective cohort study
Cardiology Dec 10, 2019
Kvakkestad KM, Gran JM, Eritsland J, et al. - Among non-ST-segment elevation myocardial infarction (NSTEMI) patients ≥ 75 years, researchers focused on short- and long-term survival in those treated with an invasive or a conservative strategy. A prospective registry included NSTEMI patients admitted to Oslo University Hospital Ulleval during 2005–2011. Using the Norwegian Cause of Death Registry, they acquired vital status until December 31, 2013. Of 2,064 NSTEMI patients ≥ 75 years (48.2% women), 1,200 (58.1%) and 864 (41.9%) patients were managed with an invasive strategy and a conservative strategy, respectively. The link of an invasive strategy with lower long-term risk was revealed following multivariate adjustment. Lower risk of long-term mortality was observed in relation to actual revascularization vs angiography only. An invasive strategy resulted in 30-day survival of 95% and 7-year survival of 47% in this real-life cohort of NSTEMI patients ≥ 75 years. Superior long-term prognosis was observed in revascularized patients. Lower short- and long-term survival was observed using a conservative strategy, likely because of selection bias and unmeasured confounding.
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