Findlay BL, Britton CJ, Glasgow AE, et al. - This study sought to explore longitudinal prescribing patterns for patients undergoing urologic surgery in the nearly 2-year time frame before and after implementation of an evidence-based opioid prescribing guideline to accurately characterize the impact on postoperative departmental practices. Researchers used historical prescribing data for adults who had undergone 21 urologic procedures at 3 academic institutions to derive a 4-tiered guideline for postoperative opioid prescribing. They used Cochran-Armitage trend tests and interrupted time series analysis to investigate for significance in the change in oral morphine equivalents (OMEs) prescribed before vs after guideline implementation. The outcomes illustrate the sustained reduction in OMEs prescribed secondary to guideline implementation and adherence by the providers in a multi-institutional follow-up prospective study of adult urologic surgery-specific evidence-based guidelines for postoperative prescribing.