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Long-term risk of hemorrhagic stroke in young patients with congenital heart disease

Stroke Jun 03, 2018

Giang KW, et al. - Given that the risk of ischemic stroke is increased in patients with congenital heart disease (CHD), the researchers explored the data on the risk of hemorrhagic stroke, including intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH) in this investigation. Between 1970 and 1993, the Swedish Patient Register was used to identify all patients who were born with a diagnosis of CHD. For this analysis, each patient was compared with 10 randomly selected controls from the general population, matched for age, sex, and county. They collected follow-up data until December 2011 for both cases and controls. Among children and young adults with CHD, the relative risk of hemorrhagic stroke was almost 8× higher than that of matched controls from the general population, although the absolute risk was low. In patients with severe nonconotruncal defects and coarctation of the aorta, the highest risk of ICH and SAH occurred.
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