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Long-term predictors of residual or recurrent cervical intraepithelial neoplasia 2-3 after treatment with a large loop excision of the transformation zone: A retrospective study

BJOG: An International Journal of Obstetrics and Gynaecology Nov 02, 2019

Fernández-Montolí ME, et al. - Researchers sought to determine the long-term risk factors that are predictive of residual/recurrent cervical intraepithelial neoplasia (CIN 2–3) and time to recurrence after large loop excision of the transformation zone (LLETZ) via retrospectively studying 242 women with CIN 2–3 treated between 1996 and 2006 and followed up until June 2016. For stratifying post-LLETZ risk, high risk-human papillomavirus and margins are supported as essential components; these components may allow personalized management of these cases. In older women, they suggest performing a large excision in order to reduce the risk given a lower risk in relation to clear margins.
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