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Long-term outcomes of video-assisted thoracoscopic lobectomy for clinical N1 non-small cell lung cancer: A propensity score-weighted comparison with open thoracotomy

Lung Cancer Nov 04, 2020

Yun JK, Park I, Kim HR, et al. - In lung cancer patients with clinical N1 (cN1) disease, researchers investigated the feasibility and long-term outcomes of video-assisted thoracic surgery (VATS). They performed a retrospective review of the records of 1,149 consecutive patients, of whom 500 patients were managed via VATS and and 649 were managed via open thoracotomy for cN1 disease from 2006 to 2016. Outcomes suggest VATS lobectomy to be feasible for patients with cN1 disease, yielding similar perioperative outcomes, oncologic efficacy, and long-term outcomes as open thoracotomy. VATS was linked with shorter hospitalization, earlier adjuvant chemotherapy, comparable complete resection rates, and equivalent dissected lymph nodes vs thoracotomy. At 5 years, overall survival and recurrence-free survival were also similar between the two groups on IPTW-adjusted analysis.

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