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Long-term outcomes of very low birth weight infants with spontaneous intestinal perforation: A retrospective case-matched cohort study

Journal of Pediatric Surgery May 19, 2019

Adant I, et al. - Researchers examined neurodevelopmental and gastrointestinal outcomes and quality of life among spontaneous intestinal perforation (SIP) survivors vs controls. In this retrospective case-matched cohort study, they included 49 infants treated for SIP in a NICU between August 1994 and April 2014. Controls and SIP patients were matched to gestational age, gender, and birth period. Findings revealed the risk of multiple disabilities among SIP survivors. They noted a worse neurodevelopmental outcome in correlation to intraventricular hemorrhage (IVH) regardless of SIP. Female gender was noted to be a protective factor against disability. The groups did not differ regarding reported quality of life and gastrointestinal comorbidities.
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