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Long-term outcomes and disease course of children with juvenile idiopathic arthritis in the ReACCh-out cohort: A two-centre experience

Rheumatology May 16, 2020

Chhabra A, Robinson C, Houghton K, et al. - The present study was performed to explore long-term results of children with Juvenile idiopathic arthritis (JIA) diagnosed in the biologic era. Researchers prospectively included chart review of patients in the Research in Arthritis in Canadian Children Emphasizing Outcomes inception cohort at two Canadian centres. According to Wallace criteria, inactive disease and remission were characterized. They enrolled 247 of 254 (97%) eligible patients diagnosed 2005–10. Relative to historical cohorts, this research implies a reduction in JIA permanent damage, a more favourable prognosis for systemic JIA and a lower progression to oligoarthritis extended category. Nevertheless, one in four patients with JIA still enter adulthood with active disease and one in two still on treatment in an era of biologic therapy.

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