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Long-term outcome after atrial correction for transposition of the great arteries

Heart Nov 15, 2018

Couperus LE, et al. - Researchers examined 76 adult patients (59% male) who underwent atrial correction according to Mustard or Senning for transposition of the great arteries (TGA), to determine long-term survival and morbidity patterns in these subjects in three periods: early (<15 years postoperatively), midterm (15–30 years postoperatively) and late (>30 years postoperatively). At 39.7 (IQR: 35.9–42.4) years following atrial correction, 82% survival was reported in adult patients with TGA. High morbidity was reported, which included supraventricular tachycardia (SVT) as most frequent adverse event. During late follow-up, the conditions that were commonly documented were ventricular arrhythmias, heart failure and surgical reinterventions. Findings also revealed the association of adverse events with depressed right ventricle function and reduced functional class.
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