Puccinelli CL, et al. - In this prospective cohort study, researchers reported long-term olfactory outcomes compared to monopoly cautery when using a cold knife upper septal limb incision technique. For categorical variables, Fisher's exact tests were conducted and for continuous variables, t tests were performed. Between March 2016 and August 2017, 22 patients (10 cold knife, 12 cautery) were enrolled. According to findings, patient University of Pennsylvania Smell Inventory Test scores were not significantly changed one year after transnasal skull-base approaches and there were no short-term or long-term differences between cold knife and cautery upper septal limb incision techniques. The research supports an individualized approach based on the preferences of the surgeon.