Huang Y, Joseph J, de Boer WB, et al. - Because the chronic liver disease is a major health burden resulting in significant liver-related morbidity and mortality, researchers assessed liver-related results of patients with various causes of chronic liver disease in Australia. From 2004 through 2015, data from 10,933 patients with chronic liver disease assessed by Hepascore (a serum fibrosis model) in Western Australia were collected. Significant differences in risk of all-cause death, liver-related death, liver transplantation, and decompensation but not hepatocellular carcinoma were observed among chronic liver diseases. Investigators found that patients with alcohol-associated liver disease had the highest 5-year cumulative risk of liver-related death and the second-highest 5-year cumulative risk of decompensation. In an analysis of patients in Western Australia, the authors discovered patients with alcohol-associated liver disease to have a significantly greater risk of decompensation and liver-related death vs patients with HCV infection, while patients with non-alcoholic fatty liver disease have significantly lower risks of either outcome.