Backdahl J, et al. - The consequence of pronounced long-term weight loss on pulse wave velocity (PWV) was comprehensively analyzed in this trial. In addition, the researchers investigated whether anthropometric/metabolic parameters and/or white adipose tissue (WAT) phenotype could speculate the change in PWV. A long-term reduction in aortic PWV (aPWV) was gained via bariatric surgery. Such an improvement could be independently speculated via subcutaneous adipocyte volume and WAT COL4A1 expression. This, in turn, indicated that subcutaneous WAT played a role in regulating aPWV.