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Long-term impact and clinical significance of living donor liver transplantation with respect to donor liver restoration and spleen size: A prospective study

American Journal of Transplantation Oct 12, 2019

Yoshino K, Taura K, Ikeno Y, et al. - In living donor liver transplantation, postoperative long-term liver restoration and splenic enlargement and their clinical significance were investigated. Researchers queried 116 donors who had donated livers more than 5 years previously to participate in this study. Calculation of the liver restoration rate and the splenic enlargement rate was done as the rate with respect to the original volume. The mean liver restoration rate of 0.99 ± 0.12 was evident. Findings indicated a higher risk for incomplete postoperative liver restoration in correlation with older age, which may be linked with a decrease in albumin more than 5 years after donation. A risk of splenic enlargement, which is associated with incomplete restoration of platelet count, was observed in correlation with right lobe donation.
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