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Long-term glycemic control and dementia risk in type 1 diabetes

Diabetes Care Oct 24, 2018

Lacy ME, et al. - Authors gauged the association of long-term glycemic control with dementia in older individuals with type 1 diabetes. The patients included in this trial were ≥50 years. They ascertained the repeated measurements of hemoglobin A1c (HbA1c), dementia diagnoses, and comorbidities from health records. Among older patients with type 1 diabetes, increased dementia risk was seen in those with majority exposure to HbA1c 8–8.9% and ≥9%. Reduced risk was seen in those with majority exposure to HbA1c 6–6.9% and 7–7.9%. For older patients with type 1 diabetes, currently recommended glycemic targets are consistent with healthy brain aging.
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