Faria J, et al. - Researchers assessed long-term cardiovascular (CV) prognosis in patients with white-coat hypertension (WCHT), taking into account night-time blood pressure (NBP). A sum of 2,659 patients had 24-hour ambulatory blood pressure (BP) monitoring: 812 had normotension (NT; 59% female), 1,230 had sustained hypertension (SHT; 56% female), and 617 had WCHT (55% female). Office BP ≥ 140/90 mmHg, daytime BP < 135/85 mmHg, and NBP < 120/70 mmHg defined WCHT. Overall, 257 CV events (36 fatal) were reported during 7.6 years of follow-up (46% strokes, 32% coronary, and 22% others): 38 in NT, 31 in WCHT, and 188 in SHT. A remarkably lower risk of CV events was observed among patients with WCHT defined by normal daytime and NBP values vs that of SHT; this attenuated risk was similar to that of NT patients. Based on these findings, the inclusion of NBP in the WCHT definition and in its prognostic stratification was recommended.