Krez A, Agarwal S, Bucovsky M, et al. - Researchers conducted this four-year prospective cohort study to examine long-term skeletal changes following Roux-en-Y gastric bypass (RYGB) in African American and Latina women. For this analysis, African American and Latina women presenting for RYGB (n = 17, mean age 44, BMI 44 kg/m²) have been followed annually for four years postoperatively. According to the results, baseline dual-energy x-ray absorptiometry Z-Scores were normal. Weight reduced ~30% at year one, then stabilized. Greater weight loss, rise in PTH, and older age were included risk factors for bone loss. After RYGB, African American and Latina women had substantial and progressive bone loss, microarchitecture deterioration and trabecular morphology. In order to understand the long-term skeletal effects of bariatric surgery in this population, further studies are essential.