Cheung C, Robert J, Tadros D, et al. - A significant rate of recurrent arrhythmic events (hazard ratio 16.9) was evident in probands in a cohort of unexplained cardiac arrest survivors and first-degree relatives.

• Analysis of cardiac arrest survivors and their first-degree relatives across 16 Canadian centers (CASPER: Cardiac Arrest Survivors with Preserved Ejection Fraction Registry).

• Participants were examined for arrhythmic events, including implantable cardioverter-defibrillator (ICD) shock or anti-tachycardia pacing (ATP).

• A median follow-up of 3.3 years revealed that 69 patients (9%) had an ICD shock or ATP with a median time-to-event of 1.0 years.

• In probands with structural/cardiomyopathy diagnoses, twice the risk of arrhythmia recurrence was observed.

• Greater probability of experiencing arrhythmic events in follow-up could be noted in patients with structural diagnoses, potentially because of a progressive disease process vs other diagnoses.