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Long non-coding RNA HCP5 facilitates cell invasion and epithelial-mesenchymal transition in oral squamous cell carcinoma by miR-140-5p/SOX4 axis

Cancer Management and Research Dec 18, 2019

Zhao J, Bai X, Feng C, et al. - In 73 paired oral squamous cell carcinoma (OSCC) tissues and their adjacent normal tissues, the HCP5 and miR-140-5p expression level was discovered in order to examine the functional role of lncRNA HCP5 in OSCC progression. Results showed that in OSCC tissues and cell lines, HCP5 expression was significantly increased. In this current research, it was shown that HCP5/miR-140-5p/SOX4 axis could be a substantial and hopeful therapeutic target for OSCC.
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