Ghosal S, Das S, Pang Y, et al. - Researchers conducted first-time in-depth characterization of long intergenic noncoding RNA (lincRNA) expression profiles and correlated findings to clinical outcomes of the disease to analyze the role of lincRNAs in the rare neuroendocrine tumors pheochromocytoma and paraganglioma (PCPG). They obtained RNA-Seq information from individuals with PCPGs and 17 other tumor types from The Cancer Genome Atlas and other published sources. According to findings, stratification of PCPG patients with a risk-score formulated utilizing multivariate analysis of lincRNA expression profiles, presence of key driver mutations, tumor location, and hormone secretion profiles exhibited significant variations in metastasis-free survival. Therefore, PCPGs show a specific lincRNA expression profile that also corresponds to the established molecular subgroups and can be a potential marker for the aggressive/metastatic PCPGs.