Pohlodek K, et al. - Given wire-guided localization (WGL) guides surgical removal of impalpable breast lesions but with potential complications, researchers tested a novel technique for localizing breast lesions in conjunction with sentinel nodes (SLNs) detection by SPIO nanoparticles; both detected using a magnetic probe. Using ultrasonographic or mammographic guidance, they placed small steel markers (Magseed) with magnetic properties in breasts. In 38 patients, 41 localization seeds were placed. They found that this technique enabled the accurate localization of breast lesions in all 38 patients. Good tolerability of the new magnetic methods, as well as their ability to avert the disadvantages of WGL, was evident in this study. These methods were acknowledged as reliable alternatives for localizing breast lesions and SLN detection. In facilities without a nuclear medicine department or where radioisotope availability is limited, the use of these novel methods may potentially allow tumor localization and SLN biopsy procedures.