Ladanyi A, et al. - Authors examined retrospectively the paraffin-embedded pretreatment biopsy samples from 45 subjects with stage III-IV resectable head and neck squamous cell carcinoma (HNSCC) by immunohistochemistry to evaluate if tumor-associated immune cells could predict the response to therapy and disease outcome in HNSCC cases receiving induction chemotherapy and cetuximab. They observed a significant correlation with response to induction chemotherapy only in the case of DC-LAMP⁺ mature dendritic cells and PD-1⁺ lymphocytes. Correlation of density of DC-LAMP⁺ cells was also noted with progression-free survival.