Madsen MH, et al. - Whether injection speed of a single dose of local anesthetic (LA) affects peripheral nerve block duration, was determined in this study involving 60 healthy adult volunteers. Researchers received a common peroneal nerve block using an ultrasound-guided catheter-based technique, followed by randomization to receive 4.0 mL of ropivacaine 0.2% with 1 of 5 injection speeds: 12, 60, 300, 600, or 1800 mL/h. The prime focus was on the duration of sensory nerve block defined by insensitivity toward cold. Duration of motor nerve block, time to onset of sensory nerve block, and grades of sensory and motor nerve block were also assessed. They found common peroneal nerve block duration remained unaffected by injection speed of LA in the range of 12 to 1800 mL/h.