Dong L, et al. - In prostate cancer tissue samples and cell lines, researchers detected terminal differentiation-induced non-coding RNA (TINCR) expression. Its relation to clinical parameters was investigated in 160 prostate cancer patients. Moreover, the biological function and molecular mechanism of TINCR was also investigated via gain-of-function and loss-of-function studies in prostate cancer cell. In prostate cancer, low-expression TINCR was detected. In prostate cancer patients, low-expression TINCR showed correlation with advanced clinical T stage, lymph node involvement, distant metastasis, high Gleason score and poor prognosis. A negative association of TINCR expression levels with TRIP13 mRNA and protein expressions was observed in prostate cancer tissues. They observed that, through suppressing TRIP13 expression, TINCR inhibited prostate cancer cell proliferation, migration and invasion.