Kihn-Alarcón AJ, et al. - In this secondary analysis, researchers focused on the extent of liver cancer in Guatemala from 2012 to 2016 as well as on the associated risk factors. They analyzed data on liver cancer mortality and morbidity as well as data regarding risk factors, such as hepatitis B virus infection, cirrhosis, and alcoholism. About 20% of cancer deaths in the country were attributed to liver cancer. The more frequent occurrence of liver cancer was reported in the population older than age 65 years old and increasing occurrence was noted in those age 30 to 44 years. In the North and West regions, they reported the occurrence of more than 25% of deaths. A decrease has been reported in the incidence of major risk factors for development of liver cancer. Compared to the incidence of liver cancer, the mortality attributed to it was higher; this implied that most patients were diagnosed at late stages. Strategies that allow earlier detection are required to attenuate the burden of liver cancer.