Segers I, Bardhi E, Mateizel I, et al. - Researchers conducted a retrospective cohort study investigating the utility of oocytes extracted from excised ovarian tissue and matured in vitro, as an adjunct for urgent fertility preservation (FP). Participants were 77 patients who underwent unilateral oophorectomy for ovarian tissue cryopreservation (OTC). In vitro maturation was performed of cumulus-oocyte complexes (COCs) obtained during ovarian tissue processing for 28–42 h. Oocytes reaching metaphase II stage were vitrified or inseminated for embryo vitrification. Overall, 1220 COCs were collected. Sixty four patients had vitrification of oocytes (6.7 ± 6.3 oocytes per patient) and 13 patients had ICSI of mature oocytes after IVM, with 2.0 ± 2.0 embryos vitrified per patient. Twelve patients came back to the clinic with a desire for pregnancy. Outcomes suggest that for FP, ovarian tissue oocyte in-vitro maturation (OTO-IVM) in combination with OTC is a valuable adjunct technique. The live birth rate per patient after OTO-IVM, ICSI and embryo transfer was 43% in this small series. The first live birth following the use of this appended technique combined with oocyte vitrification was reported by researchers.