Cho H.G, et al. – The role of random normal skin biopsy in the diagnosis of intravascular lymphoma (IVL) in adult Western patients with clinically diagnosed hemophagocytic lymphohistiocytosis (HLH), was investigated. In the setting of a single academic institution in the USA, random skin biopsies demonstrated a limited role in diagnosing IVL in adult patients with HLH. For these patients, a review of the literature emphasized the role of a full body skin exam with a selective skin biopsy