Boyko EJ, et al. - An exploration was conducted of the risk of nontraumatic lower-limb amputations associated with the same limb- and person-level factors among patients without foot ulcer. The only limb-specific risk factors for amputation were revealed to be the arterial disease and neuropathy. However, these and several person-level factors could prove to be amenable for the prevention or therapeutic interventions in order to potentially reduce diabetic amputation risk.