Lifestyle modification in older vs younger patients with coronary artery disease
Heart May 04, 2020
Jepma P, Jorstad HT, Snaterse M, et al. - In a community-based lifestyle intervention trial (n = 824), named RESPONSE-2 (The Randomised Evaluation of Secondary Prevention by Outpatient Nurse SpEcialists 2), researchers compared the treatment impact on lifestyle-related risk factors (LRFs) in older (≥ 65 years) vs younger (< 65 years) patients suffering from coronary artery disease (CAD). Experts compared nurse-coordinated referral with a comprehensive set of three lifestyle interventions (physical activity, weight reduction and/or smoking cessation) vs usual care. The proportion of patients showing improvement at 12 months follow-up (n = 711) in ≥ 1 LRF stratified by age, was the primary outcome. Findings revealed that although older patients exhibited more adverse cardiovascular risk profiles and comorbidities, nurse-coordinated referral to a community-based lifestyle intervention was identified to be at least as successful in improving LRFs in older as in younger patients. Based on these findings, it was inferred that higher age alone should not be a reason to withhold lifestyle interventions among patients suffering from CAD.
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