Zhang B, et al. - In order to explore the connection between environmental factors (usage of plastic tableware, indoor decoration, air freshener, and cooking oil fume) and ovulatory dysfunction of polycystic ovary syndrome (PCOS), lifestyles (insomnia, snoring, meat favorable diet, smoking, alcohol consumption, tea-drinking, and exercise duration) and environmental endocrine disruptor exposure of PCOS women with and without oligo-anovulation (OA) have been analyzed. Participants in the study were 2,217 infertile women diagnosed as PCOS and 279 healthy control women of reproductive age. According to findings, smoking, snoring, hyper-caloric diet, use of plastic tableware and interior decoration have been shown to be correlated with an increased risk of ovulatory dysfunction in women with PCOS. Therefore, lifestyle modification as the first-line therapy should be promoted more vigorously for PCOS especially women with OA.Hence, lifestyle modification as the first-line therapy for PCOS especially women with OA should be promoted more vigorously.