Isiozor NM, Kunutsor SK, Voutilainen A, et al. - In a middle-aged male Finnish population, findings revealed strong, inverse, and linear association of Life's Simple7 (LS7) score with the risk of total and ischemic strokes.

• Men (42–60 years) without pre-existing history of stroke at baseline (1984–1989) were included (Kuopio Ischemic Heart Disease cohort).

• For 2,520 males, LS7 was computed from American Heart Association's cardiovascular health metrics.

• Continuous decrease in the risk of both stroke outcomes (total and ischemic stroke) was evident with increasing LS7 scores across the range 2–6.

• There was 48% (hazard ratio HR: 0.52) lower risk of total stroke in men with high (5–7) LS7 vs those with low (0–2) LS7.

• A similar association was noted for the risk of ischemic stroke, with 50% (HR: 0.50) lower risk in males with high LS7 vs those with low LS7.