Abdelgadir I, Hamud A, Kadri A, et al. - This study was undertaken to ascertain the effectiveness and safety of levetiracetam in treating convulsive status epilepticus (CSE) in childhood. Researchers carried out to search PubMed, Embase, the Cochrane Central Register of Controlled Trials, and Cumulative Index to Nursing and Allied Health Literature from inception up to April 2020. They evaluated only randomized controlled trials (RCTs) that included children aged 1 month–18 years. Data assessment and extraction were conducted by two reviewers. The research included ten studies including a total of 20,637 citations. This study’s findings demonstrate that levetiracetam is comparable to phenytoin, fosphenytoin, and valproate as a second-line treatment of pediatric CSE.