Bowman ER, Cameron CMA, Avery A, et al. - In view of the observation that a wide range of illness is exhibited by people infected with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), ranging from asymptomatic infection to severe respiratory distress resulting in death, researchers here examined uninfected individuals and individuals with mild, moderate, or critical COVID-19 disease for the measures of serum biomarkers. COVID-19 individuals exhibit raised levels of monocyte activation (sCD14 and FABP4) and inflammation (TNFR1 and 2), regardless of disease severity. Among patients with critical disease, lower levels of TNFR1 and TNFR2 were reported at hospital admission in individuals who recovered from COVID-19 vs those who ultimately died.