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Levels of anti-Mullerian hormone in premenopausal women with the antiphospholipid syndrome and its association with the risk of clinical complications

Lupus Mar 14, 2019

Castillo-Martinez D, et al. - In this single-center study, 23 premenopausal female patients [10 with primary antiphospholipid syndrome (APS) and 13 with secondary APS] and 24 healthy females were studied to delineate the levels of the anti-Mullerian hormone (AMH) in females with APS and also to elaborate its relationship with the risk of clinical complications. Authors observed comparable serum AMH levels were similar in APS patients vs controls. They did not report significant variations between the primary (6.60, 5.49–8.88 ng/ml) and secondary (6.06, 3.91–7.30 ng/ml) forms of the syndrome. They recorded an inverse correlation between serum AMH levels and the aGAPSS score whereas no association was noticed with the disease-specific organ damage (DIAPS) score. They concluded no decline in ovarian reserve in premenopausal women with APS.
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