Reznik ME, et al. - Experts investigated the degree to which impaired level of consciousness (LOC) at hospital discharge was linked with outcomes after ischemic stroke, using prospectively-collected data from 2015 to 2017. Total NIHSS-LOC score at discharge, as well as subscores for responsiveness (LOC-R), orientation questions (LOC-Q), and command-following (LOC-C), were assessed. Total LOC score at discharge, as well as LOC-R and LOC-Q, correlated with unfavorable 3-month outcome. Considerably worse outcomes after ischemic stroke could be linked to impaired consciousness or disorientation at discharge.